HBV-IN-22

Names

[ CAS No. ]:
2338573-94-5

[ Name ]:
HBV-IN-22

Biological Activity

[Description]:

HBV-IN-22 (Compound LC5f) is an inhibitor of HBV DNA replication with IC50 values of 0.71 µM and 0.84 µM against wild-type and drug resistant HBV strains, respectively[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> HBV
Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis

[Target]

IC50: 0.71 µM (wild-type HBV DNA replication), 0.84 µM (drug resistant HBV DNA replication)[1]


[References]

[1]. Qiu J, et al. Discovery of novel quinazolinone derivatives as potential anti-HBV and anti-HCC agents. Eur J Med Chem. 2020 Nov 1;205:112581.

Chemical & Physical Properties

[ Molecular Formula ]:
C26H29N3O2S2

[ Molecular Weight ]:
479.66

Related Compounds