LysoTracker Red

Names

[ CAS No. ]:
231946-72-8

[ Name ]:
LysoTracker Red

Biological Activity

[Description]:

LysoTracker Red (LysoTracker Red DND-99) is a paraformaldehyde fixable probe that concentrates into acidic compartments of cells and tissues. LysoTracker Red is an indicator of cell death in a manner similar to other standard assays (Annexin, terminal dUTP nick end labeling, Nile blue sulfate, neutral red, and acridine orange)[1]. LysoTracker Red is a marker for late endosomes and lysosomes[2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Labeling of HepG2 cells with 100nM LysoTracker Red DND-99 aided examination of lysosome distribution[3].

[References]

[1]. Price OT, et al. Quantitative fluorescence of 5-FU-treated fetal rat limbs using confocal laser scanning microscopy and Lysotracker Red. Cytometry A. 2003;53(1):9-21.

[2]. Pereira LC, et al. An autophagic process is activated in HepG2 cells to mediate BDE-100-induced toxicity. Toxicology. 2017;376:59-65.

[3]. Nagahama M, et al. Cellular vacuolation induced by Clostridium perfringens epsilon-toxin. FEBS J. 2011;278(18):3395-3407.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₂₄BF₂N₅O

[ Molecular Weight ]:
399.25

Related Compounds

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