11-DEOXOJERVINEBETA-D-GLUCOSIDE

Names

[ Name ]:
11-DEOXOJERVINEBETA-D-GLUCOSIDE

[Synonym ]:
Cycloposin
(23R)-17,23-epoxy-3β-β-D-glucopyranosyloxy-veratra-5,12-diene
cycloposine

Biological Activity

[Description]:

Cycloposine is a steroidal alkaloid that can be found in the roots and rhizomes of Veratrum californicum. Cycloposine is also a teratogenic compound[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Cycloposine producs fetal cyclopia and related central nervous system malformations in sheep[2].

[References]

[1]. Chandler CM, et, al. Improved extraction and complete mass spectral characterization of steroidal alkaloids from Veratrum californicum. Nat Prod Commun. 2013 Aug;8(8):1059-64.

[2]. Keeler RF. Teratogenic compounds of Veratrum californicum (Durand). VII. The structure of the glycosidic alkaloid cycloposine. Steroids. 1969 May;13(5):579-88.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₃H₅₁NO₇

[ Molecular Weight ]:
573.76100

[ Exact Mass ]:
573.36700

[ PSA ]:
120.64000

[ LogP ]:
3.15490

Related Compounds

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