Boc-bipiperidine-ethynylbenzoic acid

Names

[ CAS No. ]:
2308497-81-4

[ Name ]:
Boc-bipiperidine-ethynylbenzoic acid

Biological Activity

[Description]:

Boc-bipiperidine-ethynylbenzoic acid is an Alkyl/ether-based PROTAC linker can be used in the synthesis of ARD-61[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

Alkyl/ether

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[References]

[1]. Lijie Zhao, et al. A highly potent PROTAC androgen receptor (AR) degrader ARD-61 effectively inhibits AR-positive breast cancer cell growth in vitro and tumor growth in vivo. Neoplasia. 2020 Oct;22(10):522-532.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₃₂N₂O₄

[ Molecular Weight ]:
412.52

[ Storage condition ]:
2-8°C

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.