NQO1 substrate

Names

[ Name ]:
NQO1 substrate

Biological Activity

[Description]:

NQO1 substrate acts as an efficient NQO1 substrate and may be a new option for the treatment of NQO1-overexpresssing drug-resistant NSCLC[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Wu X, et al. Discovery of Nonquinone Substrates for NAD(P)H: Quinone Oxidoreductase 1 (NQO1) as Effective Intracellular ROS Generators for the Treatment of Drug-Resistant Non-Small-Cell Lung Cancer. J Med Chem. 2018 Dec 27;61(24):11280-11297.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₃H₂F₂N₄O

[ Molecular Weight ]:
268.18

Related Compounds

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