4-Methylumbelliferyl 6-thio-Palmitate-β-D-Glucopyranoside

Names

[ Name ]:
4-Methylumbelliferyl 6-thio-Palmitate-β-D-Glucopyranoside

[Synonym ]:
4-Methylumbelliferyl 6-thio-palmitate-β-D-glucopyranoside

Biological Activity

[Description]:

Mu-6S-Palm-β-Glc is a fluorogenic substrate for palmitoyl-protein thioesterase (PPT). Mu-6S-Palm-β-Glc can be used for the research of neuronal ceroid lipofuscin disease in infants[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

[References]

[1]. Van Diggelen OP, et al. A rapid fluorogenic palmitoyl-protein thioesterase assay: pre- and postnatal diagnosis of INCL. Mol Genet Metab. 1999 Apr;66(4):240-4.

[2]. Boado RJ, et al. Bi-functional IgG-lysosomal enzyme fusion proteins for brain drug delivery. Sci Rep. 2019 Dec 9;9(1):18632.

Chemical & Physical Properties

[ Density]:
1.186g/cm3

[ Boiling Point ]:
738.127ºC at 760 mmHg

[ Molecular Formula ]:
C₃₂H₄₈O₈S

[ Molecular Weight ]:
592.78400

[ Flash Point ]:
400.205ºC

[ Exact Mass ]:
592.30700

[ PSA ]:
151.73000

[ LogP ]:
6.02890

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.557