MDL800

Names

[ CAS No. ]:
2275619-53-7

[ Name ]:
MDL800

[Synonym ]:
MFCD31813709

Biological Activity

[Description]:

MDL-800 is an activator of SIRT6 deacetylation, with an EC50 value of 10.3 µM[1].

[Related Catalog]:

Signaling Pathways >> Epigenetics >> Sirtuin

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Sirtuin

[Target]

SIRT6:10.3 μM (EC50)

[References]

[1]. Huang Z, et al. Identification of a cellularly active SIRT6 allosteric activator. Nat Chem Biol. 2018 Dec;14(12):1118-1126.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₁₆BrCl₂FN₂O₆S₂

[ Molecular Weight ]:
626.30

Related Compounds

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