UGM-IN-3

Names

[ Name ]:
UGM-IN-3

Biological Activity

[Description]:

UGM-IN-3 (compound 10a) is a UDP-galactopyranose mutase (UGM) inhibitor with a Kd of 66 μM. UGM-IN-3 inhibits the growth of Mycobacterium tuberculosis with a MIC value of 6.2 μg/mL[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[Target]

Kd: 66 μM (UDP-galactopyranose mutase (UGM))[1] MIC: 6.2 μg/mL (Mycobacterium tuberculosis)[1]

[References]

[1]. Carine Maaliki, et al. Synthesis and evaluation of heterocycle structures as potential inhibitors of Mycobacterium tuberculosis UGM. Bioorg Med Chem. 2020 Jul 1;28(13):115579.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₁₆INO₂

[ Molecular Weight ]:
405.23

Related Compounds

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