CRS400393

Names

[ Name ]:
CRS400393

Biological Activity

[Description]:

CRS400393 is a potent antimycobacterial agent, with MIC of 0.03, 2, and ≤ 0.12 µg/mLagainst M. abs., M. avium, M. intracellulare, and M. tuberculosis, respectively[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[Target]

Bacterial[1]

[In Vitro]

CRS400393 (Compound 43) shows no obvious effect on CYP2B6 and CYP3A4[1].

[References]

[1]. Graham J, et al. Discovery of benzothiazole amides as potent antimycobacterial agents. Bioorg Med Chem Lett. 2018 Oct 15;28(19):3177-3181.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₂₀Cl₂N₂OS

[ Molecular Weight ]:
383.34

Related Compounds

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