PRMT7-IN-1

Names

[ Name ]:
PRMT7-IN-1

Biological Activity

[Description]:

PRMT7-IN-1 (Compound 14) is a PRMT7 inhibitor with an IC50 of 2.1 μM. PRMT7-IN-1 shows anticancer activity against different cancer cells[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Epigenetics >> Histone Methyltransferase

[In Vitro]

PRMT7-IN-1 (Compound 14) shows antitumor activity with IC50 values of 2.250, 1.267, 4.4, 1 and 3.342 μM against ES-2, A2780S, Jeko-1, HO8910 and A2780/T cells, respectively[1].

[References]

[1]. Shengyong Yang, et al. A kind of compound and the preparation method and application thereof inhibiting PRMT7. CN108503623.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₂FN₅O₃

[ Molecular Weight ]:
435.45

Related Compounds

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