HKPerox-2

Names

[ Name ]:
HKPerox-2

Biological Activity

[Description]:

HKPerox-2 is an excellently selective and sensitive green fluorescent probe toward H2O2 over 30-fold other tested ROS/RNS in chemical and biological systems. HKPerox-2 is a O-methyl rhodol derivative and specifically recognize H2O2 based on a tandem payne/dakin reaction[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

HKPerox-2 is a O-methyl rhodol derivative and reaches a plateau within 30 min upon treatment of 100 μM H2O2, and the rate constants kobs is determined to be 2.0x10-2 s for HKPerox2[1]. HKPerox-2 (0-20 μM; 24 hours) is nontoxic to cells at working concentrations in RAW264.7 macrophages[1].

[References]

[1]. Sen Ye, et al. Tandem Payne/Dakin Reaction: A New Strategy for Hydrogen Peroxide Detection and Molecular Imaging. Angew Chem Int Ed Engl. 2018 Aug 6;57(32):10173-10177.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₂H₂₃NO₁₀

[ Molecular Weight ]:
581.53

Related Compounds

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