USP30 inhibitor 18

Names

[ Name ]:
USP30 inhibitor 18

Biological Activity

[Description]:

USP30 inhibitor 18 is a selective USP30 inhibitor with an IC50 of 0.02 μM. USP30 inhibitor 18 increases protein ubiquitination and accelerates mitophagy[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Deubiquitinase

[References]

[1]. Arthur F Kluge, et al. Novel highly selective inhibitors of ubiquitin specific protease 30 (USP30) accelerate mitophagy. Bioorg Med Chem Lett. 2018 Aug 15;28(15):2655-2659.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₆H₂₈FN₃O₄S

[ Molecular Weight ]:
497.58

USP30 inhibitor 18

Names

Biological Activity

Chemical & Physical Properties

Related Compounds