RORγt agonist 4

Names

[ CAS No. ]:
2241769-59-3

[ Name ]:
RORγt agonist 4

Biological Activity

[Description]:

RORγt agonist 4 (compound 14) is a potent and selective agonist of RORγt. RORγt agonist 4 significantly enhances metabolic stability. RORγt agonist 4 improves the situation of tumor models of mouse B16F10 melanoma and LLC lung adenocarcinoma[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> ROR
Research Areas >> Inflammation/Immunology

[References]

[1]. Lu L, et al. Discovery of Biaryl Amide Derivatives as Potent, Selective, and Orally Bioavailable RORγt Agonists for Cancer Immunotherapy. J Med Chem. 2023 Nov 20.  

Chemical & Physical Properties

[ Molecular Formula ]:
C26H24Cl2N2O4S

[ Molecular Weight ]:
531.45

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.