2241769-59-3

2241769-59-3 structure

Name: RORγt agonist 4
Chemical Name: RORγt agonist 4
CAS Number: 2241769-59-3
Molecular Formula: C₂₆H₂₄Cl₂N₂O₄S
Molecular Weight: 531.45
Catalog: Signaling Pathways Metabolic Enzyme/Protease ROR
Create Date: 2024-02-06 09:47:14
Modify Date: 2024-02-06 09:47:14
RORγt agonist 4 (compound 14) is a potent and selective agonist of RORγt. RORγt agonist 4 significantly enhances metabolic stability. RORγt agonist 4 improves the situation of tumor models of mouse B16F10 melanoma and LLC lung adenocarcinoma[1].

Name	RORγt agonist 4

Description	RORγt agonist 4 (compound 14) is a potent and selective agonist of RORγt. RORγt agonist 4 significantly enhances metabolic stability. RORγt agonist 4 improves the situation of tumor models of mouse B16F10 melanoma and LLC lung adenocarcinoma[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> ROR Research Areas >> Inflammation/Immunology
References	[1]. Lu L, et al. Discovery of Biaryl Amide Derivatives as Potent, Selective, and Orally Bioavailable RORγt Agonists for Cancer Immunotherapy. J Med Chem. 2023 Nov 20.

Molecular Formula	C₂₆H₂₄Cl₂N₂O₄S
Molecular Weight	531.45