2',4'-Dichloroacetophenone

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
246.7±20.0 °C at 760 mmHg

[ Melting Point ]:
33-34 °C(lit.)

[ Molecular Formula ]:
C₈H₆Cl₂O

[ Molecular Weight ]:
189.039

[ Flash Point ]:
100.9±22.3 °C

[ Exact Mass ]:
187.979568

[ PSA ]:
17.07000

[ LogP ]:
2.79

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.549

[ Water Solubility ]:
ca. 200 mg/L

Click to get detail MSDS

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H318

[ Precautionary Statements ]:
P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R22;R52/53

[ Safety Phrases ]:
S26-S39-S61

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ HS Code ]:
2914700090

Click to get detail synthetic route

Precursor

DownStream

[ HS Code ]: 2914700090

[ Summary ]:
HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%

Glutathione-dependent reductive dehalogenation of 2,2',4'-trichloroacetophenone to 2',4'-dichloroacetophenone.

Biochem. Pharmacol. 31(23) , 3885-90, (1982)

alpha-Haloketones are highly reactive compounds, which are known to undergo enzymatic reduction to methyl ketones. The objective of this research was to characterize the enzymes involved in this react...

[Synthesis of a new cyclodextrin derivative and its application as CGC chiral stationary phase in determination of enantiomeric excess].

Se Pu 20(1) , 34-6, (2002)

A new cyclodextrin (CD) derivative, 2,6-di-O-benzyl-3-O-valeryl-beta-CD, was synthesized and characterized by 1H NMR and IR. Using the beta-CD derivative as chiral stationary phase of capillary gas ch...

Microwave assisted rapid and efficient synthesis of nitrogen and sulphur containing heterocyclic compounds and their pharmacological evaluation.

Indian J. Chem. B 45(7) , 1762, (2006)

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