Apoptin-derived peptide

Names

[ CAS No. ]:
2232156-31-7

[ Name ]:
Apoptin-derived peptide

Biological Activity

[Description]:

Apoptin-derived peptide is an antitumor polypeptide with cytotoxicity. Apoptin-derived peptide promotes apoptosis and necrosis of gastric cancer (GC) cells by regulating PI3K/AKT/ARNT signaling. Apoptin-derived peptide inhibited the invasion and migration of cancer cells, and inhibited the expression and phosphorylation of the subunit p85 of PI3K, which further inhibited the PI3K/AKT pathway involved in the development of gastric cancer[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer
Signaling Pathways >> PI3K/Akt/mTOR >> PI3K
Signaling Pathways >> PI3K/Akt/mTOR >> Akt

[References]

[1]. Zhou D, et al. Apoptin-derived peptide reverses cisplatin resistance in gastric cancer through the PI3K-AKT signaling pathway [J]. Cancer Medicine, 2018, 7(4): 1369-1383.  

Chemical & Physical Properties

[ Molecular Formula ]:
C223H417N89O50S

[ Molecular Weight ]:
5177.33

Related Compounds

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