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XY028-133

Names

[ CAS No. ]:
2229974-73-4

[ Name ]:
XY028-133

Biological Activity

[Description]:

XY028-133 (example 14) is a PROTAC-based CDK4/6 degrader with anti-tumor activity, extracted from patent WO2018106870A1[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> CDK
Signaling Pathways >> PROTAC >> PROTAC

[References]

[1]. JIN, Jian， et al. COMPOSITIONS AND METHODS FOR TREATING CDK4/6-MEDIATED CANCER. Patent. US2017/065027.

Chemical & Physical Properties

[ Molecular Formula ]:
C53H67N11O7S

[ Molecular Weight ]:
1002.23

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds