BDP8900
Names
[ CAS No. ]:
2226507-05-5
[ Name ]:
BDP8900
Biological Activity
[Description]:
BDP8900 (BDP-8900) is a highly potent and selective Myotonic dystrophy-related Cdc42-binding kinase MRCK inhibitor with IC50 of 43 nM (MRCKβ), >100-fold selectivity over related ROCK1 or ROCK2; shows similar activity against MRCKα and MRCKβ; displays consistent antiproliferative effects with greatest activity in hematologic cancer cells.
[References]
References 1. Unbekandt M, et al. Cancer Res. 2018 Apr 15;78(8):2096-2114. View Related Products by Target ROCK
Chemical & Physical Properties
[ Molecular Formula ]:
C19H23N5S
[ Molecular Weight ]:
353.488
Related Compounds
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