2226507-05-5
2226507-05-5 structure
- Name: BDP8900
- Chemical Name: BDP8900
- CAS Number: 2226507-05-5
- Molecular Formula: C19H23N5S
- Molecular Weight: 353.488
- Create Date: 2020-01-20 19:18:56
- Modify Date: 2025-11-30 13:16:18
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BDP8900 (BDP-8900) is a highly potent and selective Myotonic dystrophy-related Cdc42-binding kinase MRCK inhibitor with IC50 of 43 nM (MRCKβ), >100-fold selectivity over related ROCK1 or ROCK2; shows similar activity against MRCKα and MRCKβ; displays consistent antiproliferative effects with greatest activity in hematologic cancer cells.
| Name | BDP8900 |
|---|
| Description | BDP8900 (BDP-8900) is a highly potent and selective Myotonic dystrophy-related Cdc42-binding kinase MRCK inhibitor with IC50 of 43 nM (MRCKβ), >100-fold selectivity over related ROCK1 or ROCK2; shows similar activity against MRCKα and MRCKβ; displays consistent antiproliferative effects with greatest activity in hematologic cancer cells. |
|---|---|
| References | References 1. Unbekandt M, et al. Cancer Res. 2018 Apr 15;78(8):2096-2114. View Related Products by Target ROCK |
| Molecular Formula | C19H23N5S |
|---|---|
| Molecular Weight | 353.488 |