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FT895

Names

[ CAS No. ]:
2225728-57-2

[ Name ]:
FT895

Biological Activity

[Description]:

FT895 is a potent and selective HDAC11 inhibitor with an IC50 of 3 nM.

[Related Catalog]:

Research Areas >> Inflammation/Immunology
Signaling Pathways >> Cell Cycle/DNA Damage >> HDAC
Signaling Pathways >> Epigenetics >> HDAC

[Target]

IC50: 3 nM (HDAC11)[1]


[References]

[1]. Martin MW, et al. Discovery of novel N-hydroxy-2-arylisoindoline-4-carboxamides as potent and selective inhibitors of HDAC11. Bioorg Med Chem Lett. 2018 Jul 1;28(12):2143-2147.

Chemical & Physical Properties

[ Molecular Formula ]:
C16H15F3N4O2

[ Molecular Weight ]:
352.31