Thalrugosaminine

Names

[ Name ]:
Thalrugosaminine

[Synonym ]:
5-O-Methylthalisopine
O5-methyl-thalisopine
O12'-methyl-thaligosinine
12'-O-Methylthaligosinine
O,O-DiMethylthalisopidine

Biological Activity

[Description]:

Thalrugosaminine is a benzylisoquinoline alkaloid isolated from the roots of Thalictrum minus. Thalrugosaminine shows good antibacterial activity with MIC values of 64-128 µg/ml[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Mushtaq S, et al. Isolation and characterization of three benzylisoquinoline alkaloids from Thalictrum minus L. and their antibacterial activity against bovine mastitis. J Ethnopharmacol. 2016 Dec 4;193:221-226.

Chemical & Physical Properties

[ Density]:
1.175g/cm3

[ Boiling Point ]:
739.4ºC at 760 mmHg

[ Molecular Formula ]:
C₃₉H₄₄N₂O₇

[ Molecular Weight ]:
652.77600

[ Flash Point ]:
181ºC

[ Exact Mass ]:
652.31500

[ PSA ]:
71.09000

[ LogP ]:
7.04680

[ Vapour Pressure ]:
9.92E-22mmHg at 25°C

[ Index of Refraction ]:
1.58

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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