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H-Pro-Pro-Pro-Pro-OH

Names

[ CAS No. ]:
21866-90-0

[ Name ]:
H-Pro-Pro-Pro-Pro-OH

[Synonym ]:
L-Proline, 1-[(2S)-2-pyrrolidiniumylcarbonyl]-L-prolyl-L-prolyl-, inner salt
(2S)-1-{1-[(2S)-2-Pyrrolidiniumylcarbonyl]-L-prolyl-L-prolyl}-2-pyrrolidinecarboxylate

Biological Activity

[Description]:

Tetraproline is a fragment sequence in tristetraprolin (TTP). Recruitment of the 4EHP-GYF2 cap-binding complex to tetraproline motifs of tristetraprolin promotes repression and degradation of mRNAs with AU-rich elements[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Fu R, et, al. Recruitment of the 4EHP-GYF2 cap-binding complex to tetraproline motifs of tristetraprolin promotes repression and degradation of mRNAs with AU-rich elements. RNA. 2016 Mar;22(3):373-82.  

Chemical & Physical Properties

[ Boiling Point ]:
729.8±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C20H30N4O5

[ Molecular Weight ]:
406.48

[ Flash Point ]:
395.2±32.9 °C

[ Exact Mass ]:
406.221619

[ LogP ]:
-1.50

[ Vapour Pressure ]:
0.0±5.1 mmHg at 25°C

Related Compounds