HBC525

Names

[ CAS No. ]:
2174014-64-1

[ Name ]:
HBC525

Biological Activity

[Description]:

HBC525 is a HBC-like fluorophore and a fluorogenic RNA aptamer (Kd=3.8 nM). HBC525 can be directly used as fusion tags for the imaging and tracking of cellular RNAs of interest. Fluorogenic RNA aptamers have also been used to construct various interesting dynamic RNA nanodevices for cellular target detection and imaging[1][2].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[Target]

HBC525: 491/525 nm (Ex/Em)[2]


[In Vivo]

荧光RNA适体

[References]

[1]. Chen X, et al. Visualizing RNA dynamics in live cells with bright and stable fluorescent RNAs. Nat Biotechnol. 2019;37(11):1287-1293.

[2]. Yu Q, et al. Genetically encoded RNA nanodevices for cellular imaging and regulation. Nanoscale. 2021;13(17):7988-8003.

Chemical & Physical Properties

[ Molecular Formula ]:
C19H17N3O2

[ Molecular Weight ]:
319.36

Related Compounds

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