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SHP2-IN-6

Names

[ CAS No. ]:
2169223-48-5

[ Name ]:
SHP2-IN-6

Biological Activity

[Description]:

SHP2-IN-6 is a potent SHP2 inhibitor, extracted from patent WO2017211303A1, compound 7, has an IC50 of 25.8 nM[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase

[In Vitro]

SHP2-IN-6 inhibits the proliferation of KYSE-520 cells with an IC50 of 2.17 μM[1].

[References]

[1]. Cunbo Ma, et al. Novel heterocyclic derivatives useful as shp2 inhibitors. WO2017211303A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C22H26F2N6O2S

[ Molecular Weight ]:
476.54


Related Compounds