SHP2-IN-2

Names

[ Name ]:
SHP2-IN-2

Biological Activity

[Description]:

SHP2-IN-2 is a selective, allosteric inhibitor of protein tyrosine phosphatase SHP2, preferentially inhibits SHP2 F285S over the PTP domain and allosteric site mutant; reduces the viability of MOLM14 cells with IC50 of 85 uM.

[References]

References 1. LaRochelle JR, et al. Bioorg Med Chem. 2017 Dec 15;25(24):6479-6485. View Related Products by Target Protein Phosphatase/PTP

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₁₁ClN₂O₂S

[ Molecular Weight ]:
342.797

Related Compounds

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