Navocaftor

Names

[ Name ]:
Navocaftor

[Synonym ]:
[5-(3-Amino-5-{[4-(trifluoromethoxy)phenyl]sulfonyl}-2-pyridinyl)-1,3,4-oxadiazol-2-yl]methanol
1,3,4-Oxadiazole-2-methanol, 5-[3-amino-5-[[4-(trifluoromethoxy)phenyl]sulfonyl]-2-pyridinyl]-

Biological Activity

[Description]:

Navocaftor, as a cystic fibrosis transmembrane regulator (CFTR), is a protein modulator (US 20200377491 Al, example 1)[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> CFTR

Research Areas >> Others

[Target]

CFTR[1]

[In Vitro]

Navocaftor, as a cystic fibrosis transmembrane regulator (CFTR), is a protein modulator[1].

[References]

[1]. US 20200377491 Al

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
634.0±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₅H₁₁F₃N₄O₅S

[ Molecular Weight ]:
416.33

[ Flash Point ]:
337.2±34.3 °C

[ Exact Mass ]:
416.040222

[ LogP ]:
2.50

[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C

[ Index of Refraction ]:
1.581

Related Compounds

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