Ralmitaront

Names

[ Name ]:
Ralmitaront

[Synonym ]:
1H-Pyrazole-3-carboxamide, 5-ethyl-4-methyl-1-[4-[(2S)-2-morpholinyl]phenyl]-
5-Ethyl-4-methyl-1-{4-[(2S)-2-morpholinyl]phenyl}-1H-pyrazole-3-carboxamide
Ralmitaront

Biological Activity

[Description]:

Ralmitaront (RO6889450), a potent and orally active partial agonist of the trace amine-associated receptor 1 (TAAR1), acts as a neuroleptic agent. Ralmitaront can be used for the research of neuro-related diseases, such as schizophrenia (SCZ), schizoaffective disorder, and negative symptoms[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

[References]

[1]. Linda S Brady, et al. Redirecting the revolution: new developments in drug development for psychiatry. Expert Opin Drug Discov. 2019 Dec;14(12):1213-1219.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
491.5±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₇H₂₂N₄O₂

[ Molecular Weight ]:
314.382

[ Flash Point ]:
251.0±28.7 °C

[ Exact Mass ]:
314.174286

[ LogP ]:
0.71

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.647

Related Compounds

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