PHY34

Names

[ Name ]:
PHY34

Biological Activity

[Description]:

PHY34 is a potent autophagy inhibitor with cytotoxic effects by inhibiting autophagy at a late stage (MDA-MB-435 IC50=23 nM, MDA-MB-231 IC50=5.2 nM); disrupts lysosomal function, significantly inhibits the growth of cancer cell lines in hollow fibers, as well as reduces ovarian tumor burden in a xenograft model.

[References]

References 1. Young AN, et al. Mol Cancer Ther. 2018 Jul 17. pii: molcanther.1195.2017. View Related Products by Target Autophagy

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₀H₃₀O₁₂

[ Molecular Weight ]:
582.6

[ Storage condition ]:
-20°C

Related Compounds

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