Nocistatin (human)

Names

[ Name ]:
Nocistatin (human)

Biological Activity

[Description]:

Nocistatin (human) blocks nociceptin-induced allodynia and hyperalgesia, and attenuates pain evoked by prostaglandin E2[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

[In Vitro]

Nocistatin (5.0 nmol) significantly improves the nociception (5.0 nmol)-induced impairment of learning and memory without changing motor activity or response to electric shocks[2].

[References]

[1]. E Okuda-Ashitaka, et al. Nocistatin, a peptide that blocks nociceptin action in pain transmission. Nature. 1998 Mar 19;392(6673):286-9.

[2]. M Hiramatsu, et al. Effects of nocistatin on nociceptin-induced impairment of learning and memory in mice. Eur J Pharmacol. 1999 Feb 19;367(2-3):151-5.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₄₉H₂₃₈N₄₂O₅₃S₃

[ Molecular Weight ]:
3561.93

Related Compounds

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