3'-O-Ac-dT

Names

[ Name ]:
3'-O-Ac-dT

[Synonym ]:
MFCD00056059
3'-O-ACETYLTHYMIDINE
Thymidine 3'-acetate
3'-O-acethyl thymidine
3'-O-acetyl-2'-deoxythyMidine
3'-O-Ac-thymidine
3'-acetatethyMidine
3'-O-Ac-dT

Biological Activity

[Description]:

3'-O-Acetylthymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Density]:
1.42g/cm3

[ Molecular Formula ]:
C₁₂H₁₆N₂O₆

[ Molecular Weight ]:
284.27

[ Exact Mass ]:
284.10100

[ PSA ]:
110.62000

[ Index of Refraction ]:
1.576

3'-O-Ac-dT

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds