Dermaseptin-B3

Names

[ CAS No. ]:
210890-55-4

[ Name ]:
Dermaseptin-B3

Biological Activity

[Description]:

Dermaseptin-B3 inhibits the growth of Gram-positive and Gram-negative bacteria (MIC: 1.3, 2.3, 5.0, 2.6, 2.3 μM for S. aureus, P. aeruginosa, P. aeruginosa, E. (ATCC 25922), E. (54127) respectively). Dermaseptin-B3 also inhibits tumor cell proliferation[1][2].

[Related Catalog]:

Research Areas >> Cancer
Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Charpentier S, et al. Structure, synthesis, and molecular cloning of dermaseptins B, a family of skin peptide antibiotics. J Biol Chem. 1998 Jun 12;273(24):14690-7.  

[2]. van Zoggel H, et al . Antitumor and angiostatic peptides from frog skin secretions. Amino Acids. 2012 Jan;42(1):385-95.

Chemical & Physical Properties

[ Molecular Formula ]:
C127H219N35O32S

[ Molecular Weight ]:
2780.38

Related Compounds

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