Tubulin polymerization-IN-52

Names

[ CAS No. ]:
2108615-05-8

[ Name ]:
Tubulin polymerization-IN-52

Biological Activity

[Description]:

Tubulin polymerization-IN-52 (compound SC23) is a potent tubulin polymerization inhibitor, with an IC50 of 2.9 μM[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin
Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin

[References]

[1]. Horgan MJ, et al. Identification of Novel β-Tubulin Inhibitors Using a Combined In Silico/In Vitro Approach. J Chem Inf Model. 2023 Sep 29.  

Chemical & Physical Properties

[ Molecular Formula ]:
C21H18F3N5O3

[ Molecular Weight ]:
445.39

Related Compounds