N2-(Isopropylphenoxyacetyl)-2’-O-propargylguanosine

Names

[ CAS No. ]:
2095417-23-3

[ Name ]:
N2-(Isopropylphenoxyacetyl)-2’-O-propargylguanosine

Biological Activity

[Description]:

N2-(Isopropylphenoxyacetyl)-2’-O-propargylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₂₇N₅O₇

[ Molecular Weight ]:
497.50

Related Compounds

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