Feglymycin

Names

[ CAS No. ]:
209335-49-9

[ Name ]:
Feglymycin

[Synonym ]:
feglymycin
FEGLYMYCIN

Biological Activity

[Description]:

Feglymycin is a HIV replication inhibitor. Feglymycin is also an antibiotic peptide that has antibacterial activity (MIC: 32-64 μg/mL for Staphylococcus aureus)[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> HIV

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Vértesy L, et al. Feglymycin, a novel inhibitor of the replication of the human immunodeficiency virus. Fermentation, isolation and structure elucidation. J Antibiot (Tokyo). 1999 Apr;52(4):374-82.

[2]. Dettner F, et al. Total synthesis of the antiviral peptide antibiotic feglymycin. Angew Chem Int Ed Engl. 2009;48(10):1856-61.

Chemical & Physical Properties

[ Molecular Formula ]:
C₉₅H₉₇N₁₃O₃₀

[ Molecular Weight ]:
1900.86000

[ Exact Mass ]:
1899.65000

[ PSA ]:
733.04000

[ LogP ]:
8.86910

Related Compounds

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