LEO 134310

Names

[ CAS No. ]:
2089130-74-3

[ Name ]:
LEO 134310

Biological Activity

[Description]:

LEO 134310 is a selective, non-steroidal glucocorticoid receptor (GR) agonist optimized for topical treatment., LEO 134310 showed high affinity (EC50 of 14 nM) in a GR binding assay. LEO 134310 can be used for skin diseases[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

Signaling Pathways >> GPCR/G Protein >> Glucocorticoid Receptor

[References]

[1]. Stefan Eirefelt, et al. Characterization of a novel non-steroidal glucocorticoid receptor agonist optimized for topical treatment. Sci Rep. 2022 Jan 27;12(1):1501.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₄H₄₀N₂O₈

[ Molecular Weight ]:
604.69

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.