MPO-IN-4

Names

[ CAS No. ]:
2088545-68-8

[ Name ]:
MPO-IN-4

Biological Activity

[Description]:

MPO-IN-4 (compound 12) is a potent and selective myeloperoxidase (MPO) inhibitor with an IC500 of 25 nM. MPO-IN-4 has no effect on methyl guanine methyl transferase (MGMT)[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Research Areas >> Inflammation/Immunology

[References]

[1]. Scott A Shaw, et al. Discovery and structure activity relationships of 7-benzyl triazolopyridines as stable, selective, and reversible inhibitors of myeloperoxidase. Bioorg Med Chem. 2020 Nov 15;28(22):115723.

Chemical & Physical Properties

[ Molecular Formula ]:
C12H11N5

[ Molecular Weight ]:
225.25

Related Compounds