SR 16832

Names

[ CAS No. ]:
2088135-12-8

[ Name ]:
SR 16832

[Synonym ]:
2-Chloro-N-(6-methoxy-4-quinolinyl)-5-nitrobenzamide
Benzamide, 2-chloro-N-(6-methoxy-4-quinolinyl)-5-nitro-

Biological Activity

[Description]:

SR 16832 is a dual-site, covalent and allosteric antagonist of PPARγ, inhibits cellular allosteric activation of PPARγ by rosiglitazone; a useful, complementary chemical tools for researchers to use to simultaneously inhibit both orthosteric and allosteric ligand-induced cellular activation of PPARγ.

[References]

References 1. Brust R, et al. ACS Chem Biol. 2017 Apr 21;12(4):969-978. View Related Products by Target PPAR

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
492.3±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₇H₁₂ClN₃O₄

[ Molecular Weight ]:
357.748

[ Flash Point ]:
251.5±28.7 °C

[ Exact Mass ]:
357.051636

[ LogP ]:
3.70

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.708

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.