ML 339

Names

[ CAS No. ]:
2080300-49-6

[ Name ]:
ML 339

Biological Activity

[Description]:

ML339 is a potent and selective CXCR6 (IC50 of 140 nM) antagonist that is selective (IC50 >79 μM) against CXCR5, CXCR4, CCR6 and Apelin receptor (APJ). ML339 holds potential to advance the field of prostate cancer research[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> GPCR/G Protein >> CXCR

Signaling Pathways >> Immunology/Inflammation >> CXCR

[Target]

CXCR6:140 nM (IC50)

[References]

[1]. Paul M. Hershberger, et al. Probing the CXCR6/CXCL16 Axis: Targeting Prevention of Prostate Cancer Metastasis.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₆H₃₂ClN₃O₅

[ Molecular Weight ]:
502.00

Related Compounds

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