(S)-Styrene oxide

Names

[ CAS No. ]:
20780-53-4

[ Name ]:
(S)-Styrene oxide

[Synonym ]:
(R)-Styrene oxide
(S)-Phenylethylene oxide
(R)-(+)-Styrene oxide
(R)-(epoxyethyl)benzene
(S)-Styrene oxide
(R)-2-Phenyl-oxirane
(R)-Phenyloxirane
Benzene, (epoxyethyl)-, (S)-
Benzene, (epoxyethyl)-, (R)-
(S)-(-)-Styrene oxide
R-STYRENE OXIDE
(S)-2-Phenyl-oxirane
(2R)-2-Phenyloxirane
MFCD00066210
Oxirane, 2-phenyl-, (2R)-
EINECS 202-476-7
(2S)-2-Phenyloxirane
Oxirane, 2-phenyl-, (2S)-
R-phenyloxirane
(R)-1,2-Epoxyethylbenzene
(S)-(−)-Phenyloxirane
Oxirane, phenyl-, (2R)-
(R)-(+)-Phenyloxirane
(S)-(−)-Styrene oxide
(R)-Phenylethylene oxide

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
193.9±9.0 °C at 760 mmHg

[ Melting Point ]:
-37ºC

[ Molecular Formula ]:
C₈H₈O

[ Molecular Weight ]:
120.148

[ Flash Point ]:
79.4±0.0 °C

[ Exact Mass ]:
120.057518

[ PSA ]:
12.53000

[ LogP ]:
1.61

[ Vapour Pressure ]:
0.6±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.564

[ Storage condition ]:
2~8℃

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CZ9625010

CHEMICAL NAME :: Benzene, (epoxyethyl)-, (R)-

CAS REGISTRY NUMBER :: 20780-53-4

LAST UPDATED :: 199506

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C8-H8-O

MOLECULAR WEIGHT :: 120.16

WISWESSER LINE NOTATION :: T3OTJ BR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Lung

DOSE/DURATION :: 125 umol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 278,289,1992

Safety Information

[ Symbol ]:

GHS07, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H312-H319-H350

[ Precautionary Statements ]:
P201-P280-P305 + P351 + P338-P308 + P313

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
T:Toxic;

[ Risk Phrases ]:
R21;R36;R45

[ Safety Phrases ]:
S45-S53

[ RIDADR ]:
UN 2810

[ WGK Germany ]:
3

[ RTECS ]:
CZ9625010

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2910900090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2910900090

[ Summary ]:
2910900090. epoxides, epoxyalcohols, epoxyphenols and epoxyethers, with a three-membered ring, and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles

Cloning and characterization of an epoxide hydrolase from Cupriavidus metallidurans-CH34.

Protein Expr. Purif. 79(1) , 49-59, (2011)

A putative epoxide hydrolase-encoding gene was identified from the genome sequence of Cupriavidus metallidurans CH34. The gene was cloned and overexpressed in Escherichia coli with His(6)-tag at its N...

Simultaneous determination of aromatic acid metabolites of styrene and styrene-oxide in rat urine by gas chromatography-flame ionization detection.

J. Anal. Toxicol. 36(5) , 312-8, (2012)

A convenient and reliable gas chromatographic method was developed for the simultaneous determination of six aromatic acid metabolites of styrene and styrene-oxide in rat urine; i.e., benzoic (BA), ph...

Solvent and TMEDA effects on the configurational stability of chiral lithiated aryloxiranes.

Chemistry 17(29) , 8216-25, (2011)

The employment of hexane/N,N,N',N'-tetramethylethylenediamine (TMEDA) dramatically hinders the racemization of those lithiated styrene oxides (trifluoromethyl-, chloro-, and phenylthio-substituted) th...