Coniferaldehyde

Names

[ CAS No. ]:
20649-42-7

[ Name ]:
Coniferaldehyde

[Synonym ]:
2-Propenal, 3-(4-hydroxy-3-methoxyphenyl)-, (2E)-
3-methoxy-4-hydroxycinnamaldehyde
(2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enal
coniferaldehyde
Ferulyl aldehyde
2-Propenal, 3-(4-hydroxy-3-methoxyphenyl), (E)-
4-HYDROXY-3-METHOXYCINNAMALDEHYDE
(2E)-3-(4-Hydroxy-3-methoxyphenyl)acrylaldehyde
coniferyl aldehyde
Coniferylaldehyde

Biological Activity

[Description]:

trans-Coniferyl aldehyde (compound 2) is a natural compound isolated from the buds of clove (Syzygium aromaticum).trans-Coniferyl aldehyde suppresses 63% of the UV mutable gene expression at 1.20 μM, and with an ID50 value of 0.76 μM,and has the antimutagenicactivities against furylfuramide, Trp-P-1, and activated Trp-P-1[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis

[References]

[1]. Miyazawa M,et al. Antimutagenic activity of phenylpropanoids from clove (Syzygium aromaticum). J Agric Food Chem. 2003;51(22):6413-6422.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
338.8±27.0 °C at 760 mmHg

[ Melting Point ]:
80-82ºC(lit.)

[ Molecular Formula ]:
C₁₀H₁₀O₃

[ Molecular Weight ]:
178.185

[ Flash Point ]:
136.8±17.2 °C

[ Exact Mass ]:
178.062988

[ PSA ]:
46.53000

[ LogP ]:
1.35

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.593

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-37/39-36

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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