4,4'-PCB
Names
[ CAS No. ]:
2050-68-2
[ Name ]:
4,4'-PCB
[Synonym ]:
Biphenyl,4,4'-dichloro
p,p'-dichlorobiphenyl
4,4'-Dichloro-1,1'-biphenyl
Biphenyl, 4,4'-dichloro-
1,1'-Biphenyl, 4,4'-dichloro-
PCB 15
p,p-Dcbp
4,4'-PCB
MFCD00013641
4,4'-Dichlorobiphenyl
PCB No 15
1,1'-Biphenyl,4,4'-dichloro
EINECS 218-095-4
4,4'-Dichloro-biphenyl
1-chloro-4-(4-chlorophenyl)benzene
4.4'-Dichlorobiphenyl
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
318.0±17.0 °C at 760 mmHg
[ Melting Point ]:
288℃
[ Molecular Formula ]:
C12H8Cl2
[ Molecular Weight ]:
223.098
[ Flash Point ]:
145.2±14.5 °C
[ Exact Mass ]:
222.000305
[ LogP ]:
5.12
[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C
[ Index of Refraction ]:
1.594
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DV3912500
- CHEMICAL NAME :
- 1,1'-Biphenyl, 4,4'-dichloro-
- CAS REGISTRY NUMBER :
- 2050-68-2
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C12-H8-Cl2
- MOLECULAR WEIGHT :
- 223.10
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 150 mg/kg/3D-I
- TOXIC EFFECTS :
- Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other esterases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other hydrolases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 700 mg/kg/7D-I
- TOXIC EFFECTS :
- Liver - hepatitis (hepatocellular necrosis), zonal
MUTATION DATA
- TEST SYSTEM :
- Insect - Drosophila melanogaster
- DOSE/DURATION :
- 1 mmol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 342,61,1995
Safety Information
[ Symbol ]:
GHS02, GHS07, GHS08, GHS09
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H225-H304-H315-H336-H373-H410
[ Precautionary Statements ]:
P210-P261-P273-P301 + P310-P331-P501
[ Hazard Codes ]:
F: Flammable;Xi: Irritant;
[ Risk Phrases ]:
R11
[ Safety Phrases ]:
16-26-33-36
[ RIDADR ]:
UN 2315
[ RTECS ]:
DV3912500
[ Packaging Group ]:
II
[ Hazard Class ]:
9
[ HS Code ]:
2903999010
Synthetic Route
Customs
[ HS Code ]: 2903999010
[ Summary ]:
2903999010 2,3,3',4,5,6-hexachloro-1,1'-biphenyl。supervision conditions:89(articles on the list of prohibited export goods,articles on the list of prohibited import goods)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:5.5%。general tariff:30.0%
Articles
Sci. Total Environ. 101(3) , 263-8, (1991)
Anaerobic cultures containing 4,4'-dichlorobiphenyl (4,4'CB) were inoculated with various environmental samples. The degradation of the substrate was followed by gas chromatographic analysis. Three of...
Possible molecular targets of halogenated aromatic hydrocarbons in neuronal cells.Biochem. Biophys. Res. Commun. 280(5) , 1372-7, (2001)
Halogenated aromatic hydrocarbon including polychlorinated biphenyls (PCBs) are persistent and bioaccumulative environmental toxicants. Although health effects associated with exposure to these chemic...
The effect of chlorine substitution on the disposition of polychlorinated biphenyls following dermal administration.Toxicol. Appl. Pharmacol. 216(1) , 157-67, (2006)
The fate of selected polychlorobiphenyls (PCBs) was investigated following single dermal administration (0.4 mg/kg) to determine the effects of chlorine content and position on the disposition of PCBs...