6-cyanopurine
Names
[ CAS No. ]:
2036-13-7
[ Name ]:
6-cyanopurine
[Synonym ]:
Purine-6-carbonitrile
EINECS 218-005-3
6-Purinecarbonitrile
6-Cyano-purin
6-Cyanoadenine
6-Cyan-purin
MFCD00005569
6-Cyanopurine
Purine,6-cyano
1H-Purine-6-carbonitrile
Chemical & Physical Properties
[ Density]:
1.56g/cm3
[ Boiling Point ]:
529.5ºC at 760mmHg
[ Melting Point ]:
186-189ºC(lit.)
[ Molecular Formula ]:
C6H3N5
[ Molecular Weight ]:
145.12200
[ Flash Point ]:
161.9ºC
[ Exact Mass ]:
145.03900
[ PSA ]:
78.25000
[ LogP ]:
0.22458
[ Vapour Pressure ]:
0.00496mmHg at 25°C
[ Index of Refraction ]:
1.852
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UO7518000
- CHEMICAL NAME :
- Purine-6-carbonitrile
- CAS REGISTRY NUMBER :
- 2036-13-7
- LAST UPDATED :
- 198502
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C6-H3-N5
- MOLECULAR WEIGHT :
- 145.14
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Parenteral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 80 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 71,618,1982
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H312-H315-H319-H332-H335
[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
R20/21/22
[ Safety Phrases ]:
26-36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
UO7518000
[ HS Code ]:
2933990090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Antimicrob. Agents Chemother. 54 , 5329-36, (2010)
Bacillus anthracis, the etiological agent of anthrax, has a dormant stage in its life cycle known as the endospore. When conditions become favorable, spores germinate and transform into vegetative bac...
Efficient conversion of 6-cyanopurines into 6-alkoxyformimidoylpurines.Org. Biomol. Chem. 2(7) , 1019-24, (2004)
An extremely simple method for the selective synthesis of 9-aryl and 9-alkyl 6-alkoxy or 6-alkoxyformimidoylpurines from the corresponding 6-cyanopurines is described. The reaction is carried out with...
Soluble aldehyde dehydrogenase and metabolism of aldehydes by soybean bacteroids.J. Bacteriol. 151(3) , 1473-84, (1982)
A soluble aldehyde dehydrogenase (EC 1.2.1.3) was partially purified from Rhizobium japonicum bacteroids and from free-living R. japonicum 61A76. The enzyme was activated by NAD+, NADH, and dithiothre...