Purine
Names
[ CAS No. ]:
120-73-0
[ Name ]:
Purine
[Synonym ]:
7H-Purine
X 128
{Imidazo[4,5-d]pyrimidine}
imidazopyrimidine
b-Purine
1,3-Diazolo[4,5-d]-1,3-diazine
6H-Imidazo[4,5-d]pyrimidine
9H-PURINE
MFCD00079221
β-Purine
1H-Purine
Purine
Isopurine
{6H-Imidazo[4,5-d]pyrimidine}
EINECS 204-421-2
Imidazo[4,5-d]pyrimidine
Chemical & Physical Properties
[ Density]:
1.5±0.1 g/cm3
[ Boiling Point ]:
424ºC at 760mmHg
[ Melting Point ]:
214-217 °C(lit.)
[ Molecular Formula ]:
C5H4N4
[ Molecular Weight ]:
120.112
[ Flash Point ]:
225.4ºC
[ Exact Mass ]:
120.043594
[ PSA ]:
54.46000
[ LogP ]:
-0.37
[ Vapour Pressure ]:
0.0976mmHg at 25°C
[ Index of Refraction ]:
1.738
[ Storage condition ]:
2-8°C
[ Water Solubility ]:
400 g/L (20 ºC)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UO7450000
- CHEMICAL NAME :
- Purine
- CAS REGISTRY NUMBER :
- 120-73-0
- LAST UPDATED :
- 199504
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C5-H4-N4
- MOLECULAR WEIGHT :
- 120.13
- WISWESSER LINE NOTATION :
- T56 BM DN FN HNJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD10 - Lethal Dose
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Blood - changes in bone marrow (not otherwise specified)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 156 mg/kg/8W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors
MUTATION DATA
- TYPE OF TEST :
- DNA damage
- TEST SYSTEM :
- Mammal - species unspecified Lymphocyte
- DOSE/DURATION :
- 50 mmol/L
- REFERENCE :
- PNASA6 Proceedings of the National Academy of Sciences of the United States of America. (National Academy of Sciences, Printing & Pub. Office, 2101 Constitution Ave., Washington, DC 20418) V.1- 1915- Volume(issue)/page/year: 48,686,1962 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7178 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1822 (estimated) No. of Female Employees: 272 (estimated)
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Safety Phrases ]:
S22-S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
UO7450000
[ HS Code ]:
2933990090
Synthetic Route
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
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There is high interest in the discovery of early diagnostic biomarkers of Alzheimer's disease, for which metabolomics exhibits a great potential. In this work, a metabolomic approach based on ultrafil...
The presence of fucogalactoxyloglucan and its synthesis in rice indicates conserved functional importance in plants.Plant Physiol. 168 , 549-60, (2015)
The predominant structure of the hemicellulose xyloglucan (XyG) found in the cell walls of dicots is a fucogalactoXyG with an XXXG core motif, whereas in the Poaceae (grasses and cereals), the structu...