6-Nitroveratraldehyde

Names

[ CAS No. ]:
20357-25-9

[ Name ]:
6-Nitroveratraldehyde

[Synonym ]:
4,5-dimethoxy-2-nitro-benzaldehyde
Benzaldehyde,4,5-dimethoxy-2-nitro
3,4-Dimethoxy-6-nitrobenzaldehyde
6-Nitroveratraldehyde
2-nitro-4,5-dimethoxybenzaldehyde
DNA-Dependent Protein Kinase Inhibitor
DMNB
EINECS 243-762-1
MFCD00007134
DNA-PK Inhibitor

Biological Activity

[Description]:

DMNB (6-Nitroveratraldehyde), a precursor, can be used for the synthesis no-carrier-added 6-[18F]fluoro-L-DOPA (6-FDOPA). No-Carrier-Added (NCA) 6-[18F]fluoro-L-dopa (6-FDOPA) is being produced routinely for PET investigations of dopaminergic systems[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

[References]

[1]. Zhang Lan, et al. Preparation of 6-[¹⁸F]fluoro-L-DOPA and its biodistribution in normal and unilateral PD model rats. Nuclear Science and Techniques, 13(4), 244-250.

[2]. Reddy GN, et al. Quality assurance and quality control methods for animal and human applications of no-carrier-added 6-[18F]fluorodopa for PET investigations of dopaminergic systems. Appl Radiat Isot. 1993;44(7):993-998.

Chemical & Physical Properties

[ Density]:
1.312 g/cm3

[ Boiling Point ]:
390.8ºC at 760 mmHg

[ Melting Point ]:
133.2-134.5 °C

[ Molecular Formula ]:
C₉H₉NO₅

[ Molecular Weight ]:
211.17100

[ Flash Point ]:
194.3ºC

[ Exact Mass ]:
211.04800

[ PSA ]:
81.35000

[ LogP ]:
1.94770

[ Vapour Pressure ]:
2.59E-06mmHg at 25°C

[ Index of Refraction ]:
1.571

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
DMSO: 22 mg/mL

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
UN 2811 6.1/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
GY8410000

[ HS Code ]:
2913000090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2913000090

[ Summary ]:
HS: 2913000090 halogenated, sulphonated, nitrated or nitrosated derivatives of products of heading 2912 Educational tariff:17.0% Tax rebate rate:9.0% Regulatory conditions:none Most favored nation tariff:5.5% General tariff:30.0%

Articles

An improved synthesis of no-carrier-added (NCA) 6-[¹⁸ F] Fluoro-l-DOPA and its remote routine production for PET investigations of dopaminergic systems. Reddy GN, et al.

Appl. Radiat. Isot. 44(4) , 645-49, (1993)

o-Nitroaryl-bis (5-methylfur-2-yl) methanes as Versatile Synthons for the Synthesis of Nitrogen-Containing Heterocycles. Butin AV, et al.

Molecules 2(4) , 62-8, (1997)

Related Compounds

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