HKOH-1

Names

[ CAS No. ]:
2031170-96-2

[ Name ]:
HKOH-1

Biological Activity

[Description]:

HKOH-1 is a highly sensitive and selective fluorescent probe for detecting endogenous hydroxyl radicals[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

HKOH-1 shows absorption peaks at 500 nm. In absence of •OH, HKOH-1 is non-fluorescent[1]. HKOH-1r (0.1-50 μM; 24 h) shows negligible or no cytotoxicity in both RAW264.7 cells and Hela cells[1]. HKOH-1r (5 μM; 30 min) detects endogenous •OH in the flow cytometry platform in RAW264.7 cells[1].

[References]

[1]. Xiaoyu Bai, et al. HKOH-1: A Highly Sensitive and Selective Fluorescent Probe for Detecting Endogenous Hydroxyl Radicals in Living Cells. Angew Chem Int Ed Engl. 2017 Oct 9;56(42):12873-12877.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₆H₁₂Cl₂I₂O₆

[ Molecular Weight ]:
745.08

Related Compounds

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