NF 340

Names

[ CAS No. ]:
202982-98-7

[ Name ]:
NF 340

[Synonym ]:
2,6-Naphthalenedisulfonic acid, 4,4'-[carbonylbis[imino(4-methyl-3,1-phenylene)carbonylimino]]bis-, sodium salt (1:4)
Tetrasodium 4,4'-{carbonylbis[imino(4-methyl-3,1-phenylene)carbonylimino]}di(2,6-naphthalenedisulfonate)

Biological Activity

[Description]:

NF340 is a potent and selective P2Y11 receptor antagonist. NF340 inhibits the activity of P2Y11R by completely combining with ATP-binding amino acid residues. NF340 ameliorates inflammation in human fibroblast-like synoviocytes and can be used for rheumatoid arthritis research[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> P2Y Receptor

Research Areas >> Inflammation/Immunology

[Target]

P2Y11 receptor[1]

[References]

[1]. Feng Gao, et al. P2Y11 receptor antagonist NF340 ameliorates inflammation in human fibroblast-like synoviocytes: An implication in rheumatoid arthritis. IUBMB Life. 2019 Oct;71(10):1552-1560.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₇H₂₆N₄Na₄O₁₅S₄

[ Molecular Weight ]:
986.84

[ Exact Mass ]:
985.986816

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.