M-6-G TRIFLUOROACETATE-HYDRATE
Names
Chemical & Physical Properties
[ Density]:
1.64g/cm3
[ Boiling Point ]:
731.6ºC at 760mmHg
[ Melting Point ]:
237-240°C (dec.)
[ Molecular Formula ]:
C23H27NO9
[ Molecular Weight ]:
461.46200
[ Flash Point ]:
396.3ºC
[ Exact Mass ]:
461.16900
[ PSA ]:
149.15000
[ Vapour Pressure ]:
1.8E-22mmHg at 25°C
[ Index of Refraction ]:
1.731
[ Storage condition ]:
−20°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- LZ6500700
- CHEMICAL NAME :
- Glucopyranosiduronic acid, 7,8-didehydro-4,5-alpha-epoxy-3-hydroxy-17-methylmorp hinan-6- alpha-yl-, beta-D-
- CAS REGISTRY NUMBER :
- 20290-10-2
- LAST UPDATED :
- 198909
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C23-H27-N-O9
- MOLECULAR WEIGHT :
- 461.51
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 432 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 67(4),97P,1971
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H312-H317-H332
[ Precautionary Statements ]:
P280
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
20/21/22-43
[ Safety Phrases ]:
36
[ RIDADR ]:
UN 1993C 3 / PGIII
[ WGK Germany ]:
3
[ RTECS ]:
LZ6500700
Articles
Life Sci. 109(2) , 104-10, (2014)
Morphine is extensively metabolized to neurotoxic morphine-3-glucuronide (M3G) and opioid agonist morphine-6-glucuronide (M6G). Due to these different roles, interindividual variability and co-adminis...
[Rapid opiate detoxification under anesthesia (RODA)].Rev. Med. Liege. 68(5-6) , 298-302, (2013)
Rapid Opiate Detoxification under Anesthesia (RODA) involves the use of opiate antagonists combined with anesthesia and pharmacotherapy to reduce withdrawal symptoms. The aim of our study was to measu...
[Blood-brain barrier transport of opioid analgesics].Yakugaku Zasshi 131(10) , 1445-51, (2011)
Opioid analgesics exhibit cationic properties under physiological conditions, and the mechanism underlying permeation of the blood-brain barrier thus cannot be fully explained by simple diffusion alon...