BMS 191011

Names

[ CAS No. ]:
202821-81-6

[ Name ]:
BMS 191011

[Synonym ]:
Bms-a
HMS3269L09
UNII-LW7MXS978N
3-[(5-Chloro-2-hydroxyphenyl)methyl]-5-[4-(trifluoromethyl)phenyl]-1,3,4-oxadiazol-2(3H)-one

Biological Activity

[Description]:

BMS-191011 (BMS-A) is an opener of the large-conductance, Ca2++-activated potassium (maxi-K) channel, effective in stroke models[1].

[Related Catalog]:

Research Areas >> Neurological Disease

Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel

[References]

[1]. Romine JL, et al. 3-[(5-Chloro-2-hydroxyphenyl)methyl]-5-[4-(trifluoromethyl)phenyl ]-1,3,4-oxadiazol-2(3H)-one, BMS-191011: opener of large-conductance Ca(2+)-activated potassium (maxi-K) channels, identification, solubility, and SAR. J Med Chem. 2007 Feb 8;50(3):528-42.

Chemical & Physical Properties

[ Density]:
1.516g/cm3

[ Boiling Point ]:
443.965ºC at 760 mmHg

[ Molecular Formula ]:
C₁₆H₁₀ClF₃N₂O₃

[ Molecular Weight ]:
370.71

[ Flash Point ]:
222.302ºC

[ Exact Mass ]:
370.03300

[ PSA ]:
68.26000

[ LogP ]:
3.92940

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.598

[ Storage condition ]:
2-8℃

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H413

[ Precautionary Statements ]:
P301 + P310

[ RIDADR ]:
UN 2811 6.1 / PGIII

[ HS Code ]:
2934999090

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.