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Trometamol(Tris),for molecular biology-d11

Names

[ CAS No. ]:
202656-13-1

[ Name ]:
Trometamol(Tris),for molecular biology-d11

[Synonym ]:
MFCD00145480
Tris-d11 solution
TRIS-d11

Biological Activity

[Description]:

Trometamol(Tris),for molecular biology-d11 is the deuterium labeled Trometamol(Tris),for molecular biology[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

Chemical & Physical Properties

[ Density]:
1.137 g/mL at 25ºC

[ Boiling Point ]:
219-220ºC10 mm Hg(lit.)

[ Melting Point ]:
162-165ºC(lit.)

[ Molecular Formula ]:
C4D11NO3

[ Molecular Weight ]:
132.20300

[ Exact Mass ]:
132.14300

[ PSA ]:
86.71000

[ Index of Refraction ]:
n20/D 1.346

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

Related Compounds