DEQUALINIUM IODIDE
Names
[ CAS No. ]:
2019-42-3
[ Name ]:
DEQUALINIUM IODIDE
[Synonym ]:
1,1'-(Decane-1,10-diyl)bis(4-amino-2-methylquinolinium) diiodide
Quinaldinium,1,1'-decamethylenebis(4-amino-,diiodide
Dequalinium iodide
Dequalinium Diiodide
1,1'-Decamethylenebis(4-aminoquinaldinium iodide)
EINECS 217-964-5
Quinolinium,1,1'-(1,10-decanediyl)bis(4-amino-2-methyl-,diiodide
MFCD00191973
Chemical & Physical Properties
[ Melting Point ]:
>300ºC (dec.)(lit.)
[ Molecular Formula ]:
C30H40I2N4
[ Molecular Weight ]:
710.47400
[ Exact Mass ]:
710.13400
[ PSA ]:
59.80000
[ LogP ]:
1.34060
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VA0705000
- CHEMICAL NAME :
- Quinaldinium, 1,1'-decamethylenebis(4-amino-, diiodide
- CAS REGISTRY NUMBER :
- 2019-42-3
- LAST UPDATED :
- 199603
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C30-H40-N4.2I
- MOLECULAR WEIGHT :
- 710.54
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 21 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 8,110,1956
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
36/37/38
[ Safety Phrases ]:
26-36
[ RIDADR ]:
NONH for all modes of transport
[ RTECS ]:
VA0705000
Articles
Curr. Probl. Dermatol. 40 , 36-47, (2011)
Vaginally applied antimicrobial agents are widely used in the vagina in women with lower genital tract infections. An 'antimicrobial' is a general term that refers to a group of drugs that are effecti...
Dequalinium induces cytotoxicity in human leukemia NB4 cells by downregulation of Raf/MEK/ERK and PI3K/Akt signaling pathways and potentiation of specific inhibitors of these pathways.Leuk. Res. 38(7) , 795-803, (2014)
Delocalized lipophilic cation dequalinium (DQA) selectively accumulates in mitochondria and displays anticancer activity in different malignancies. Our previous studies indicate a DQA-induced cytotoxi...
N-palmitoyl-ethanolamine (PEA) induces peripheral antinociceptive effect by ATP-sensitive K+-channel activation.J. Pharmacol. Sci. 118(2) , 156-60, (2012)
Although the antinociceptive effects of N-palmitoyl-ethanolamine (PEA) were first characterized nearly 50 years ago, the identity of the mechanism that mediates these actions has not been elucidated. ...